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Clinical Research Nurse II - Oncology

Location: Boston, Massachusetts

Date Posted: 30 Jun, 2026


Position Summary
The Clinical Research Nurse II (CRN II) reports directly to the Medical Director of the Cancer Clinical Trials Program and the Administrative Director in Hematology and Medical Oncology. This role is primarily responsible for performing clinical and patient-facing tasks for patients enrolled in clinical trials. The CRN II collaborates with providers to identify eligible patients, reviews consent forms, discusses trial requirements, and ensures compliance with study protocols during patient visits. The nurse also provides clinical perspective to regulatory coordinators to facilitate trial activation.

As a clinically facing research staff member, the CRN II will spend the majority of time in clinic, following and evaluating approximately 16–24 patients per week.

Key Responsibilities
Administrative
  1. Assist principal investigators with protocol review and development
  2. Collaborate on quality assurance and protocol-specific materials

Research
  1. Recruit and register patients for clinical trials
  2. Coordinate scheduling of labs, imaging, admissions, and visits
  3. Collaborate with coordinators and disease group staff to complete trials

Clinical
  1. Coordinate study enrollment, treatment, and study requirements
  2. Collaborate with care teams including infusion, radiation, and surgical nurses
  3. Educate patients and families on protocols, adapting to age and cultural needs
  4. Order and monitor specimens and administer medications as necessary
  5. Document in charts and communicate findings to investigators and physicians
  6. Provide protocol training and serve as a resource to the healthcare team
  7. Monitor patient safety and regulatory compliance

Professional Development
  1. Identify areas for growth and set professional goals
  2. Engage in professional organizations locally and nationally
  3. Participate in committees and prepare reports, articles, and presentations

Required Qualifications
  1. Current Registered Nurse license
  2. Bachelor of Science in Nursing (BSN) preferred; Associate Degree accepted
  3. Experience in clinical research and oncology
  4. Strong communication, organizational, and patient care skills

Preferred Qualifications
  1. Prior experience in cancer clinical trials
  2. Familiarity with regulatory compliance and trial activation

Education: Masters Degree